Al-Hilal overcame Al-Ittihad 2-0 in their game in the 21st round of Prince Mohammed bin Salman League for Professionals.
Bafetimbi Gomis and Salim El-Dossari scored Al-Hilal goals in the 67th and 82nd minutes.
Al-Hilal extended their lead at the top of the league by reaching 52 points, 9 points ahead of Al-Nasr the second with a game in hand, while Al-Ittihad lie 15th with 15 points.
Al-Hilal handed their hosts their first loss in 2019 after five games saw two wins and three draws for Jeddah team.
At Al-Hazm Stadium Al-Ittifaq gained a 1-1 draw with the hosts.
The two goals scored from penalty kicks awarded in the space of three minutes.
Wagner Alemao put Al-Hazm in front in the 67th minute before Cristian Guanca levelled the result in the 70th minute.
Al-Ittifaq's total moved up to 28 points in the 8th spot, while Al-Hazm reached 23 points in the 12th place on the table.
The round games will be resumed on Friday with three matches, between Al-Taween and Al-Batin, Al-Qadsya against Al-Shabab and finally Al-Wahda versus Ohod.
At King Abdullah Sport City Stadium, Al-Taween the fifth with 33 points will host Al-Batin the 13th with 18 points.
Al-Qadsya the 11th with 23 points will face Al-Shabab the third on the table with 37 points at Prince Saud Bin Jalawi Sport City Stadium.
At King Abdul Aziz Sport City Stadium, Al-Wahda the 7th with 31 points will face Ohod the 16th wil 12 points.
The matchday games will be concluded on Saturday with two matches between Al-Raed and Al-Faisaly and Al-Nasr versus Al-Fayhaa.
Al-Raed the 10th with 24 points will meet Al-Faisaly the 8th with 27 points, at King Abdullah Sport City Stadium.
Al-Nasr the second with 43 points, will host Al-Fayhaa the 14th with 16 points, at Prince Faisal Bin Fahd Stadium.
The matchday games were kicked off on Wednesday with Al-Fateh 2-1 win over their visitors Al-Ahli.